Heritability of Immunity Traits and Resistance of Atlantic Salmon against the Sea Louse Caligus rogercresseyi
نویسندگان
چکیده
The immune response of Atlantic salmon to sea lice has been extensively studied, but we still do not know the mechanisms by which some fish become resistant and others not. In this study, estimated heritabilities three key proteins associated with innate immunity resistance Salmo salar against louse Caligus rogercresseyi. particular, quantified abundance 2 pro-inflammatory cytokines, Tnfα Il-8, an antioxidant enzyme, Nkef, in skin gill tissue from 21 families 268 individuals indirect ELISA. This covers a wide parasite load range low or (mean ± SE = 8.7 0.9) high susceptible 43.3 2.0). Our results showed that had higher levels Nkef than their gills skin, although Il-8 was fish, while no significant differences were found skin. Furthermore, moderate very heritable genetic variation for (h2 skin: 0.96 0.14 gills: 0.97 0.11) 0.53 0.17 0.32 0.14), 0.22 0.12 ns 0.09 0.08 ns). work provides evidence protein expressions are highly related salmon.
منابع مشابه
Disease Resistance in Atlantic Salmon (Salmo salar): Coinfection of the Intracellular Bacterial Pathogen Piscirickettsia salmonis and the Sea Louse Caligus rogercresseyi
BACKGROUND Naturally occurring coinfections of pathogens have been reported in salmonids, but their consequences on disease resistance are unclear. We hypothesized that 1) coinfection of Caligus rogercresseyi reduces the resistance of Atlantic salmon to Piscirickettsia salmonis; and 2) coinfection resistance is a heritable trait that does not correlate with resistance to a single infection. M...
متن کاملCathepsin Gene Family Reveals Transcriptome Patterns Related to the Infective Stages of the Salmon Louse Caligus rogercresseyi
Cathepsins are proteases involved in the ability of parasites to overcome and/or modulate host defenses so as to complete their own lifecycle. However, the mechanisms underlying this ability of cathepsins are still poorly understood. One excellent model for identifying and exploring the molecular functions of cathepsins is the marine ectoparasitic copepod Caligus rogercresseyi that currently af...
متن کاملRNA-Seq Analysis Using De Novo Transcriptome Assembly as a Reference for the Salmon Louse Caligus rogercresseyi
Despite the economic and environmental impacts that sea lice infestations have on salmon farming worldwide, genomic data generated by high-throughput transcriptome sequencing for different developmental stages, sexes, and strains of sea lice is still limited or unknown. In this study, RNA-seq analysis was performed using de novo transcriptome assembly as a reference for evidenced transcriptiona...
متن کاملEvidence for the Induction of Key Components of the NOTCH Signaling Pathway via Deltamethrin and Azamethiphos Treatment in the Sea Louse Caligus rogercresseyi
The extensive use of organophosphates and pyrethroids in the aquaculture industry has negatively impacted parasite sensitivity to the delousing effects of these antiparasitics, especially among sea lice species. The NOTCH signaling pathway is a positive regulator of ABC transporter subfamily C expression and plays a key role in the generation and modulation of pesticide resistance. However, lit...
متن کاملLessons from sea louse and salmon epidemiology.
Effective disease management can benefit from mathematical models that identify drivers of epidemiological change and guide decision-making. This is well illustrated in the host-parasite system of sea lice and salmon, which has been modelled extensively due to the economic costs associated with sea louse infections on salmon farms and the conservation concerns associated with sea louse infectio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biology
سال: 2023
ISSN: ['2079-7737']
DOI: https://doi.org/10.3390/biology12081078